Clinical study on prophylactic efficacy of ondansetron against post-operative nausea and vomiting in children undergoing laparoscopic surgery for inguinal hernia.

Prospective clinical study on prophylactic efficacy of ondansetron against post-operative nausea and vomiting in children undergoing laparoscopic surgery for inguinal hernia. - Prospective clinical study on prophylactic efficacy of ondansetron against post-operative nausea and vomiting in children undergoing laparoscopic surgery for inguinal hernia.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000052211

Enrollment

550

Registered

2023-09-15

Start date

2023-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric inguinal hernia

Interventions

Prophylactic administration of ondansetron (peri-operative period) Placebo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Children undergoing elective laparoscopic surgery for inguinal hernia (under 15 years old, ASA-PS from 1 to 2) in Saitama Municipal Hospital. 2. Patients (and/or their guardian) who provided an explanation of the study plan before surgery, fully understood the objectives of the study, and obtained written consent.

Exclusion criteria

Exclusion criteria: 1. Patients who are allergic to any of the drugs used in this study.

Design outcomes

Primary

Measure	Time frame
Post-operative nausea and vomiting (within 24 hours after surgery)	—

Countries

Japan

Contacts

Public ContactNorihito Nakamura

Saitama Municipal Hospital Department of critical care medicine

gomachan4761@energy.ocn.ne.jp0488734111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026