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Additional impact of pancreatic juice cytology via endoscopic nasal pancreatic tube for the diagnosis of high-grade pancreatic intraepithelial neoplasia/ invasive pancreatic cancer without visible tumor by endoscopic ultrasound

Additional impact of pancreatic juice cytology via endoscopic nasal pancreatic tube for the diagnosis of high-grade pancreatic intraepithelial neoplasia/ invasive pancreatic cancer without visible tumor by endoscopic ultrasound - Usefulness of pancreatic juice cytology via endoscopic nasal pancreatic tube for the diagnosis of early pancreatic cancer

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000052193
Enrollment
22
Registered
2023-09-13
Start date
2023-06-29
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

high-grade pancreatic intraepithelial neoplasia/ invasive pancreatic cancer without visible tumor by endoscopic ultrasound

Interventions

None listed

Sponsors

Oita San-ai Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: pancreatic juice cytology for patients with highly suspected small pancreatic cancer without visible mass by endoscopic ultrasound from May 2015 to April 2023.

Exclusion criteria

Exclusion criteria: First, PJC for the diagnosis of suspected intraductal papillary mucinous neoplasm (IPMN) with high-grade dysplasia/carcinoma derive from IPMN was excluded because of the different nature of tumor. PJC for suspected PDAC with visible mass by EUS due to the failure diagnosis of EUS-FNAB was also excluded. Patients with PJC positive results who underwent imaging follow-up less than one year without surgical resection and patients with PJC negative results who underwent imaging follow-up less than five years without surgical resection were excluded as undiagnosed cases, considering the progress nature/period of HG-PanIN and invasive PDAC.

Design outcomes

Primary

MeasureTime frame
Comparison of sensitivity, spesificity, accuracy, and area under curve of pancreatic juice cytology via endoscopic nasal pancreatic tube and those of single pancreatic juice cytology during endoscopic retrograde pancreatography.

Countries

Japan

Contacts

Public ContactRyota Sagami

Oita San-ai Medical Center Department of Gastroenterology

sagami1985@yahoo.co.jp0975411311

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026