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Single-center prospective pilot intervention study on clinical indicators influencing weight loss in allogeneic hematopoietic stem cell transplantation

A prospective study on clinical indicators that affect the rate of weight loss in allogeneic hematopoietic stem cell transplantation - Prospective study on weight loss rate in allogeneic hematopoietic stem cell transplantation

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000052185
Enrollment
20
Registered
2023-09-12
Start date
2024-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hematopoietic tumor

Interventions

Nutritional intervention

Sponsors

Shizuoka Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients undergoing allo-SCT using bone marrow catastrophic conditioning (busulfan 6.4 mg/kg, melphalan 140 mg/m2, whole body irradiation: multiple times 8 Gy) at Shizuoka Cancer Center Blood and Stem Cell Transplant Department. Performance status (PS): PS 0 to 2 before transplantation. Persons who provide explanations to patients themselves using explanatory documents and obtain written consent from the patients themselves. Persons who are between 18 and 70 years of age at the time of obtaining consent. Persons whose body mass index is 18.5 or more and less than 25.0 kg/m2 at the time of obtaining consent.

Exclusion criteria

Exclusion criteria: Simultaneous active multiple cancers. Case with severe complications. Cases of metastasis to the central nervous system with symptoms. Case of pregnancy or breastfeeding. Case with mental disorder. Cases who answered that they were concerned about the amount of intake recorded on food tags. Cases judged to be inappropriate by the attending physician.

Design outcomes

Primary

MeasureTime frame
Identification of the optimal required calorimetric method (Evaluate the relationship between the sufficiency rate obtained by dividing the total calorie supply during the period by the 5 types of basal metabolic calorie and the weight loss rate, and identify the optimal necessary calorie measurement method.)

Countries

Japan

Contacts

Public ContactTakashi Aoyama

Shizuoka Cancer Center Dietary Department

t.aoyama@scchr.jp0559895222

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026