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Correlation between changes in intestinal microbiota and defecatory function before and after radical resection of right- and left-sided colon cancer.

Correlation between changes in intestinal microbiota and defecatory function before and after radical resection of right- and left-sided colon cancer. - Correlation between changes in intestinal microbiota and defecatory function before and after radical resection of right- and left-sided colon cancer.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000052095
Enrollment
120
Registered
2023-11-01
Start date
2023-11-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colon cancer

Interventions

None listed

Sponsors

Saitama Medical University International medical center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients diagnosed with primary colorectal cancer 2) Patients who are 20 years of age or older at the time of consent 3) Patients whose gastrointestinal surgeon determines that surgical therapy is necessary 4) Patients whose written consent for this study has been obtained 5) Patients who will undergo ileal resection or right hemicolectomy of the colon for right-sided colorectal cancer or left hemicolectomy, descending colon resection, or sigmoid colon resection for left-sided colorectal cancer

Exclusion criteria

Exclusion criteria: 1) Patients with multiple cancers 2) Patients with a history of autoimmune bowel disease 3) Patients with a history of severe hepatic dysfunction 4) Patients with a history of severe renal dysfunction 5) Patients receiving antimicrobial agents on a regular basis 6) Patients who received preparations that affect intestinal bacteria such as intestinal antiflatulents and probiotics preoperatively. 7) Patients who receive chemotherapy (antimetabolites, platinum, molecular-targeted drugs, immune checkpoint inhibitors) preoperatively and postoperatively. 8) Patients who receive chemotherapy (antimetabolite, platinum, molecular-targeted drug, immune checkpoint inhibitor) before and after surgery

Design outcomes

Primary

MeasureTime frame
Pre- and postoperative voiding function

Secondary

MeasureTime frame
Pre- and postoperative intestinal flora

Countries

Japan

Contacts

Public ContactSohei Akuta

Saitama Medical University International medical center Gastrointestinal Surgery

sohei.3402@gmail.com042-984-4111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026