A multicenter prospective study to assess energy expenditure by indirect calorimetry in critically ill patients in the acute phase

A multicenter prospective study to assess energy expenditure by indirect calorimetry in critically ill patients in the acute phase - A study to assess energy expenditure by indirect calorimetry in critically ill patients

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000052094

Enrollment

144

Registered

2023-09-04

Start date

2024-05-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult critically ill patients admitted to an intensive care unit and requiring mechanical ventilation

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who meet all of the following criteria 1. Patients aged 18 years or older at the time of consent 2. Patients who are anticipated to require mechanical ventilation in an intensive care unit for more than 48 hours and treatment for more than 7 days 3. Patients who have received adequate explanations regarding participation in this study and have provided written consent voluntarily based on an adequate understanding of this study

Exclusion criteria

Exclusion criteria: Patients who meet any of the following criteria 1. Patients who are considered difficult to use indirect calorimetry with conditions (e.g. pneumothorax) or receiving treatments (e.g. gas exchange with ECMO, FiO2 > 0.7, PEEP > 15 cmH2O, max airway pressure > 30 cmH2O) 2. Patients who are deemed ineligible by the principal investigator

Design outcomes

Primary

Measure	Time frame
The optimal amount of energy according to the phase of critical illness	—

Secondary

Measure	Time frame
1. Differences between mREE and REE calculated by Harris-Benedict formula or ESPEN guideline formula(25 kcal/kg) in each phase 2. Subgroup analysis of the primary outcome according to age, sex, and severity 3. Analysis of mREE variation in each phase to identify metabolic patterns according to age, sex, and pathophysiology	—

Countries

Japan

Contacts

Public ContactTaku Oshima

Chiba University Hospital Department of Emergency and Critical Care Medicine

t_oshima@chiba-u.jp043-222-7171

Outcome results