An exploratory prospective observational study on the effects of gut microbiota and diet on acute postoperative pain.

An exploratory prospective observational study on the effects of gut microbiota and diet on acute postoperative pain. - An exploratory prospective observational study on the effects of gut microbiota and diet on acute postoperative pain.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000052053

Enrollment

Registered

2023-09-01

Start date

2023-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rotator cuff injury

Interventions

None listed

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Adult patients aged 18 years or older undergoing specoscopic shoulder joint surgery under general anaesthesia at Chiba University Hospital, female patients who cooperated in the questionnaire survey and gave consent to submit a stool specimen.

Exclusion criteria

Exclusion criteria: Patients with chronic inflammatory diseases such as rheumatoid arthritis Patients with chronic pain Patients using strong opioids before surgery Patients who received antibiotics within 1 month Patients under 18 years of age Non-consenting

Design outcomes

Primary

Measure	Time frame
Intestinal bacterial alpha diversity (Shannon Index)	—

Secondary

Measure	Time frame
Analgesic use in the first post-operative week, length of hospital stay, analgesic use in the first post-operative month, post-operative nausea and vomiting, gut bacterial composition, gut bacterial metabolites	—

Countries

Japan

Contacts

Public ContactKOTONO YAMADA

Chiba University Hospital Department of Anesthesiology

kotono1004@yahoo.co.jp+81-43-226-2303

Outcome results