None listed
Conditions
Interventions
Period II, Intake of mineral water.
Sequence group2: Period I, intake of mineral water
Period II
Intake of electrolyte replenishment drink.
Sponsors
IMEQRD Co., Ltd.
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1)Healthy male aged 20 years or older on the date of informed consent. 2)Those who are 50kg or over of body weight and BMI within from 18.5 kg/m^2 or over to 25.0 kg/m^2 or less. 3)Those who can stay overnight from the day before the test. 4)Those who can input data into the logbook using electronic tools such as PCs, or smartphones. 5)Those who can make self-judgment and are voluntarily giving written informed consent.
Exclusion criteria
Exclusion criteria: 1)Have donated 400 mL of whole blood 3 months before the screening. 2)Have donated 200 mL of whole blood or blood components 1 month before the screening. 3)The sum of donated blood volume in the study and donation within 12 months before the screening test is over 1200 mL. 4)Have been comprehensively judged by the principal investigator to require treatment for dehydration based on clinical indicators at the screening test. 5)Who participated in a study involving the use of other foods or drugs, or the application of cosmetics or drugs within 4 months before obtaining consent, or who will participate in other studies while participating in this study. 6)Currently undergoing treatment with some kind of drug or herbal medicine. 7)Currently taking over-the-counter drugs, quasi-drugs and foods or supplements with specified health claims or who cannot withdraw these during the study period. 8)Heavily drinkers (40g or more as pure alcohol). 9)Have unstable lifestyles such as shift workers, and night shifts. 10)Have a smoking habit (less than 1 year after quitting smoking). 11)May change lifestyles such as long-term travel during the study. 12)Have a habit go to a sauna (at least over once a month), or have never experienced a sauna. 13)Have extensive burn scars. 14)Have tattoos. 15)Have Claustrophobia and unable to be in sauna. 16)Have drug addiction, or have been drug addicted. 17)Have difficulty with blood donation, or have experienced bad mood, deterioration of physical condition, or vasovagal reflex due to blood collection in the past. 18)Have a history or current medical history of heatstroke. 19)Have a history or current medical history of severe liver, kidney, heart, respiratory, endocrine, metabolic diseases, etc. 20)Those who are judged by the principal investigator to be inappropriate as research subjects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body weight | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood tests: White blood cells, red blood cells, hemoglobin, hematocrit, platelet, Na, K, Cl, Ca, total protein, albumin, blood urea nitrogen, creatinine, glucose, serum osmolality Urine tests: Urine volume, urine specific gravity, urine osmolality, Na, K, Cl, Mg, Ca, creatinine, urine urea nitrogen, inorganic phosphorus ion, urine protein, urine sugar, urobilinogen, bilirubin, occult blood Fractional excretion of sodium, body water balance, body electrolyte balance , body temperature, blood pressure, pulse, general symptom questionnaire | — |
Countries
Japan
Contacts
Public ContactRyo Uchida
Ajinomoto Co., Inc. Functional Ingredients Development Group, Wellness Value Creation Center, Institute of Food Sciences
Outcome results
None listed