Healthy subjects
Conditions
Interventions
Receiving 27 mg of plant extract as active component daily group
Placebo group
Sponsors
NIPPN Corporation
University of Tsukuba
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Able-bodied persons aged 20 to 64 at the time of obtaining the consent form 2. Persons with no history of hypersensitivity to grape and/or dextrin 3. Have not been a smoker for at least one year 4. No history of epilepsy, diabetes, cerebrovascular disease, cardiovascular disease, cancer, or paralysis 5. No daily use of medications that may affect this study (Listerine or other antibacterial mouth rinses, antibiotics, or gargles) 6. No oral diseases for which treatment is available 7. Those who have not undergone dental maintenance (plaque and tartar removal) within the past 3 months 8. Have 20 or more teeth 9. Not pregnant, not intending to become pregnant during the examination period, and not breast-feeding 10. Those who have not participated or are not currently participating in any other clinical research within 3 months 11. Those who fully understand the content of this study and are able to commute to the site of this study on their own
Exclusion criteria
Exclusion criteria: 1. Those who use health foods or supplements that may affect this study within 3 months 2. Those who used medicines (antibacterial oral rinses and antibiotics such as Listerine, and gargles) that may affect this study within 2 weeks prior to the start of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral Environment Indices | — |
Countries
Japan
Contacts
Public ContactKyoko Shimazu
NIPPN Corporation Central Research Laboratory, Innovation Center
Outcome results
None listed