Impact of Periodontal Treatment on Clinical Outcomes in Patients with Coronary Artery Disease Undergoing Percutaneous Coronary Intervention

Impact of Periodontal Treatment on Clinical Outcomes in Patients with Coronary Artery Disease Undergoing Percutaneous Coronary Intervention: A Prospective Study (PERIO-PCI) - PERIO-PCI

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000051921

Enrollment

300

Registered

2023-09-01

Start date

2023-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The study will target patients over 20 years of age with coronary artery disease (CAD) who undergo percutaneous catheter intervention (PCI) and who give informed consent to participate in this study. CAD includes stable angina as well as acute coronary syndromes (ACS) which consist of ST-elevation myocardial infarction, non-ST-elevation myocardial infarction, and unstable angina.

Exclusion criteria

Exclusion criteria: 1) Currently undergoing treatment for periodontal disease (PD) 2) Patients with cardiogenic shock, or hemodynamically or electrically unstable acute coronary syndrome (ACS) 3) Positive for COVID-19 4) Currently pregnant or breastfeeding 5) Carrying infectious diseases such as hepatitis virus or HIV.

Design outcomes

Primary

Measure	Time frame
The composite endpoint that includes cardiovascular death, non-fatal myocardial infarction, target lesion revascularization, and non-target lesion revascularization at 24 months	—

Secondary

Measure	Time frame
Inflammatory markers at 12 months (high-sensitivity CRP, IL-6, TNF-alpha)	—

Countries

Japan

Contacts

Public ContactMakoto Araki

Tokyo Medical and Dental University Cardiology Division

maraki.cvm@tmd.ac.jp+81-3-3813-6111

Outcome results