Major depressive disorder
Conditions
Interventions
Smartphone cognitive behavioral therapy
Sponsors
Kyoto University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 18 years of age or older Patients with diagnosed o major depressive disorder and moderate to severe depressive symptoms who did not respond to an optimal dose of one or more antidepressants for a sufficient period, or who were unable to receive adequate antidepressants due to intolerance Patients with treatment response (HAMD-17 >50% improvement from baseline) or remission (HAMD-17 <7) after 3-6 weeks of rTMS Familiarity with smartphone operation Able to read, write, and communicate in Japanese Voluntary consent to participate in the study
Exclusion criteria
Exclusion criteria: Acute suicidal ideation Cannot read or write Japanese
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Completion rate of smartphone cognitive behavioral therapy app at 6 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in PHQ-9 at 1, 2, 3, 4, 5, and 6 weeks Changes in GAD-7, ISI, SWEMWBS, cognitive and behavioral skills, social functioning, and EQ-5D-5L at 3 and 6 weeks CSQ-3 at 6 weeks Questionnaire on lesson progress, usage, and burden of the app at 6 weeks | — |
Countries
Japan
Contacts
Public ContactYuki Matsuda
Kyoto University Graduate School of Medicine/School of Public Health Dept of Health Promotion and Human Behavior
Outcome results
None listed