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A multicenter validation study to create a model to predict Parkinson's disease motor symptom scores from blink information in patients with Parkinson's disease.

A multicenter validation study to create a model to predict Parkinson's disease motor symptom scores from blink information in patients with Parkinson's disease. - A multicenter validation study to create a model to predict Parkinson's disease motor symptom scores from blink information in patients with Parkinson's disease.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000051871
Enrollment
100
Registered
2023-08-09
Start date
2023-08-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson disease

Interventions

None listed

Sponsors

Juntendo University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Age between 20 and 90 years old at the time of obtaining consent. 2) Patients who have been diagnosed with Parkinson's disease (clinically confirmed or almost clinically certain) according to the "Clinical Diagnostic Criteria for MDS Parkinson's Disease (PD) (2015)". (3) Patients who have received a thorough explanation of their participation in this study, and who have given their free and voluntary written consent based on a thorough understanding of the study.

Exclusion criteria

Exclusion criteria: (1) Patients with Parkinson's syndrome other than Parkinson's disease (2) Patients under treatment for dry eye (iii) Patients with cognitive impairment that makes it difficult to conduct the study (4) Patients with any of the following complications Psychiatric disorders (depression, bipolar disorder, schizophrenia, etc.) Other serious complications (cerebrovascular disease, cardiac disease, chronic respiratory disease, uncontrolled hypertension, diabetes mellitus, etc.) (5) Other patients who are deemed inappropriate as research subjects by the principal investigator.

Design outcomes

Primary

MeasureTime frame
Concordance between motor symptom scores inferred from blink information and actual MDS-UPDRS Part 3 scores obtained by neurologists.

Secondary

MeasureTime frame
Percentage of concordance between dyskinesia estimated from blink information and actual dyskinesia.

Countries

Japan

Contacts

Public ContactNoriko Nishikawa

Juntendo University School of Medicine Department of Neurology

n.nishikawa.ts@juntendo.ac.jp03-3813-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026