A multicenter prospective cohort study for determining gastroesophageal junction (GOJ) in esophagogastroduodenoscopy (EGD) under sedation

A multicenter prospective cohort study for determining gastroesophageal junction (GOJ) in esophagogastroduodenoscopy (EGD) under sedation - GOJ-S

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000051868

Enrollment

500

Registered

2023-08-09

Start date

2023-08-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patients in whom GOJ zone will be observed in EGD under sedation (2) Informed consent for participating in this study is conducted after the explanation

Exclusion criteria

Exclusion criteria: (1) Patients who refuse for participating in this study (2) Patients with a history of surgical resection in upper gastrointestinal tract (3) Patients who underwent endoscopic treatment in the GOJ zone (4) Patients with tumors in the GOJ zone (5) Patients who are judged as inappropriate for participating in this study by the researchers

Design outcomes

Primary

Measure	Time frame
The rate of identifying DEPV in white light imaging	—

Secondary

Measure	Time frame
1) Difference of the rates of identifying DEPV among each sedation type 2) Difference of the rates of identifying DEPV between patients with and without hiatal hernia 3) Difference of the rates of identifying DEPV in patients with and without reflux esophagitis (Los Angeles classification N, M, A, B, C, and D) 4) Difference of the rates of identifying DEPV between patients with and without Helicobacter pylori infection and among degree of endoscopic gastric atrophy 5) Difference of the rates of identifying DEPV among white light imaging and various type of image enhanced endoscopy (NBI, BLI, LCI, TXI, and RDI) 6) Difference of the rates of identifying DEPV between transoral and transnasal endoscopy and among various type of endoscope 7) The length of palisade vessels which can be seen underneath the columnar epithelium 8) Concordance rate between DEPV and PEGV (and condition of the concordance) 9) Intraobserver and interobserver agreement for visibility of DEPV 10) Factors associated with no identification of DEPV	—

Measure

Time frame

1) Difference of the rates of identifying DEPV among each sedation type 2) Difference of the rates of identifying DEPV between patients with and without hiatal hernia 3) Difference of the rates of identifying DEPV in patients with and without reflux esophagitis (Los Angeles classification N, M, A, B, C, and D) 4) Difference of the rates of identifying DEPV between patients with and without Helicobacter pylori infection and among degree of endoscopic gastric atrophy 5) Difference of the rates of identifying DEPV among white light imaging and various type of image enhanced endoscopy (NBI, BLI, LCI, TXI, and RDI) 6) Difference of the rates of identifying DEPV between transoral and transnasal endoscopy and among various type of endoscope 7) The length of palisade vessels which can be seen underneath the columnar epithelium 8) Concordance rate between DEPV and PEGV (and condition of the concordance) 9) Intraobserver and interobserver agreement for visibility of DEPV 10) Factors associated with no identification of DEPV

—

Countries

Japan

Contacts

Public ContactWaku Hatta

Tohoku University Graduate School of Medicine Division of Gastroenterology

waku-style@festa.ocn.ne.jp0227177171

Outcome results