Study of the efficacy of third-line eradication therapy with sitafloxacin in patients who failed Helicibacter pylori eradication

Study of the efficacy of third-line eradication therapy with sitafloxacin in patients who failed Helicibacter pylori eradication. - Study of the efficacy of third-line eradication therapy with sitafloxacin in patients who failed Helicibacter pylori eradication.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000051852

Enrollment

Registered

2023-08-07

Start date

2023-08-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori infection

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who have been confirmed to be unsuccessful in the second-line H. pylori eradication therapy by our hospital or a previous physician, and who have undergone the third-line eradication at our hospital and who have done an eradication determination test.

Exclusion criteria

Exclusion criteria: (1) Pregnant or lactating patients (2) Patients with allergy to VPZ, MNZ, or STFX (3) Patients with severe liver, kidney, or heart dysfunction (4) Patients whose physician deems inappropriate (5) Patients who are allergic to penicillin and have used VPZ-MNZ-STFX triple therapy as primary or secondary eradication therapy. (6) Patients diagnosed with autoimmune gastritis (7) Patients whose eradication decision could not be confirmed

Design outcomes

Primary

Measure	Time frame
Success rate of H. pylori eradication in third-line Helicobacter eradication therapy (7-day VPZ-MNZ-SFTX triple therapy)	—

Secondary

Measure	Time frame
Incidence of adverse events Factors influencing H. pylori eradication failure	—

Countries

Japan

Contacts

Public ContactKazuhiro Mizukami

Faculty of Medicine, Oita University Department of Gastroenterology

mizkaz0809@oita-u.ac.jp097-586-6193

Outcome results