Healthy subject
Conditions
Interventions
Duration: 12 weeks Test food: Nucleotide containing capsule Administration: Take two capsules per day at breakfast. * If you forget to take a dose, take it within the same day and do not carry ov
Sponsors
DRC Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Age between 20 and 60 (2) Male and female (3) Subjects who are aware of dry skin (4) Subjects who only use 1-2 items of lotion or milky lotion after washing their face (after bathing) (5) Subjects who have received a sufficient explanation of the purpose and content of this study, have the ability to consent, and who voluntarily apply for participation after having a good understanding of the study, and who are able to give written consent to participate in this study.
Exclusion criteria
Exclusion criteria: 1. Subjects who have urticaria, inflammation, eczema, trauma, acne, pimples, warts, blemishes, etc. or their traces on the evaluation site 2. Subjects with a history or current history of atopic dermatitis, or with atopic predisposition 3. Subjects who have received cosmetic treatment at the evaluation site or plan to receive it during the study period 4. Subjects who use creams, gels, all-in-one products, beauty devices, or packs on the evaluation site 5. Subjects who continuously use drugs, health foods, supplements, skin care products, cosmetics, quasi-drugs that advocate or emphasize efficacy related to the efficacy examined in this study 6. Subjects who have performed the following within the past 4 weeks or plan to do so during the study period a) Changed or started health foods, basic cosmetics or sunscreen agents used on the evaluation sites b) Exposed to ultraviolet rays beyond daily life c) Participated in other human trials d) Received a special skin care treatment on the evaluation site 7. Subjects who work night shifts or day and night shifts 8. Subjects who are undergoing treatment at medical institutions for the treatment or prevention of disease, or those who are judged to require treatment 9. Subjects with a history of serious diseases of sugar metabolism, lipid metabolism, liver function, renal function, heart, circulatory system, respiratory system, endocrine system, immune system, nervous system, psychiatric disease, alcohol or drug dependence. 10. Subjects who are at risk of developing food allergies 11. Subjects who have a smoking habit 12. Subjects who are likely to develop seasonal allergic symptoms such as hay fever and may use pharmaceuticals 13. Subjects who are pregnant, breastfeeding, or wish to become pregnant during the study period 14. Subjects who are judged by the principal investigator to be unsuitable for study participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin viscoelasticity by Cutometer | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) Stratum corneum water content by Corneometer (2) Dermal thickness by DermaLab (3) Wrinkle grade on the outer corner of the eyes by visual and photographic evaluation (4) Wrinkle area percentage, total average depth of wrinkles, average depth of maximum wrinkles, and maximum depth of maximum wrinkles on the corner of the eyes using replica (5) Blemishes, wrinkles, pores, color irregularities, porphyrins, hidden spots, melanin index, hemoglobin index by VISIA imaging (6) TEWL by VAPOSCAN (7) IL-1RA/IL-1 alpha, cell area, degree of multiple exfoliation, carbonylated proteins, and Involucrin/Nile red stain using tape-stripped stratum corneum (8) Questionnaire | — |
Countries
Japan
Contacts
Public ContactYuri Okano
CIEL CO., LTD. CIEL CO., LTD.
Outcome results
None listed