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Efficacy of antipsychotics and antihistamines on delirium: a systematic review

Efficacy of combined antipsychotic and antihistamine therapy in cancer patients with delirium: a systematic review - Efficacy of combined antipsychotic and antihistamine therapy: a systematic review

Status
Active, not recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000051808
Enrollment
Unknown
Registered
2023-08-03
Start date
2023-09-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer

Interventions

None listed

Sponsors

IMSUT Hospital, the Institute of Medical Science, The University of Tokyo
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients with cancer(more than or equal to 80%) 2.Patients with delirium 3.Trials including combined antipsychotic and antihistamine therapy The study design to be considered for inclusion is as follows: 1.If there were at least two randomized controlled trial (RCT)s, inclusion was completed. 2.If there were less than 2 RCTs, we included non-RCTs or observational studies with control groups. 3.If there were no RCTs/non-RCTs/observational studies with control groups, single-arm observational studies were considered for inclusion.

Exclusion criteria

Exclusion criteria: 1.Duplicate publications 2.Conference proceedings

Design outcomes

Primary

MeasureTime frame
Change in severity of delirium before and after treatment initiation—

Secondary

MeasureTime frame
somnolence, extrapyramidal signs and QT prolongation—

Countries

Japan

Contacts

Public ContactTetsuya Ito

IMSUT Hospital, the Institute of Medical Science, The University of Tokyo Department of Palliative Medicine and Advanced Clinical Oncology

rachmaninov0531@gmail.com03-3443-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026