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A Retrospective Study to Explore Early Screening Indicators for AD pathology

A Retrospective Study to Explore Early Screening Indicators for AD pathology - A Retrospective Study to Explore Early Screening Indicators for AD pathology

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000051776
Enrollment
200
Registered
2023-08-31
Start date
2023-09-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild Cognitive impairment Healthy adult volunteers

Interventions

None listed

Sponsors

Oita University
Lead Sponsor
Eisai Co., Ltd.
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Subjects of this study are participants in Usuki Cohort (the cohort of local elderly residents in Usuki City, Oita Prefecture) and those who visited Oita University Hospital, and they meet all the following inclusion criteria. 1. MCI who fulfilled the diagnostic criteria of Petersen (CDR 0.5), or healthy adult volunteers who did not fulfill the diagnostic criteria of Petersen (CDR 0). 2. Subjects undergone amyloid PET ([11C]PiB: Pittsburgh compound-B) testing.

Exclusion criteria

Exclusion criteria: Subjects of this study are participants in Usuki Cohort (the cohort of local elderly residents in Usuki City, Oita Prefecture) and those who visited Oita University Hospital, and they meet all the following inclusion criteria. 1. Subjects with some missing data. 2. Subjects who have stated their willingness to participate in the research. 3. Any other subjects who are judged to be ineligible by the principal investigator or sub-investigator.

Design outcomes

Primary

MeasureTime frame
To construct a prediction model for the presence or absence of Amyloid-beta accumulation in the brain using machine learning based on clinical information (variables) collected retrospectively, and to evaluate its prediction accuracy.

Countries

Japan

Contacts

Public ContactNoriyuki Kimura

Oita University Faculty of Medicine Department of Neurology

noriyuki@oita-u.ac.jp097-586-5814

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026