chronic diarrhea
Conditions
Interventions
None listed
Sponsors
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with diarrhea symptoms defined in the Guidelines for the Diagnosis and Treatment of Bowel Movements (Chronic Constipation Syndrome/Chronic Diarrhea Syndrome) 2023: "Soft and watery stools with increased frequency of defecation". Outpatients attending Keio University Hospital. Patients who have given consent for this study. Patients must be 18 years of age or older.
Exclusion criteria
Exclusion criteria: Patients with organic disease as a possible cause of diarrheal symptoms. Other patients who are deemed inappropriate for inclusion in the study by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage reduction in daily stool frequency with diarrhea medications | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of disease background and symptoms with efficacy of diarrhea medications (lower gastrointestinal endoscopy findings, abdominal X-ray findings, abdominal CT findings, enterography findings, blood test findings, rectal manometry findings, colon function test findings, blood pressure, abdominal and mental symptoms at presentation (GI symptoms questionnaire, HADS questionnaire, WPAI:GH questionnaire, Bristol stool Scale)). Association of symptoms with quality of life, labor productivity, anxiety and depression in diarrhea. Safety of diarrhea medications. | — |
Countries
Japan
Contacts
Public ContactHideki Mori
Keio University School of Medicine Division of Gastroenterology and Hepatology, Department of Internal Medicine
Outcome results
None listed