Autism Spectrum Disorder
Conditions
Interventions
None listed
Sponsors
National Center for Child Health and Development
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. the child is between 1 and 3 years of age at the time consent is obtained 2. the father, mother, and the infant must be living together at the time consent is obtained 3. the parents or guardians of the subject child have agreed to the content of this study and have given their written consent to participate in the study 4. the guardian of the subject child is able to understand the Japanese language described in the consent document and the questionnaire.
Exclusion criteria
Exclusion criteria: 1. the parent or guardian of the research subject child is under 18 years of age 2. parents or guardians of the research subject child who require a surrogate guardian; 3. the research subject child has already been diagnosed with ASD 3. the research subject child has already been diagnosed with ASD 4. the research subject child has a severe mental or physical disability 5. Other subjects who are deemed inappropriate to participate in this study by the Principal Investigator or a Research Supervisor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Validity: Area under the curve (AUC of ROC) of ASD diagnoses assessed based on the TASI Japanese version against the presence or absence of autism spectrum disorder/autism spectrum disorder (ASD) as assessed by the ADOS-2, ADI-R or PARS-TR - Agreement (Cohen's Kappa coefficient) between the presence or absence of ASD assessed based on the DSM-5 and the ASD diagnosis assessed based on the TASI Japanese version by a team of experts skilled in ASD clinical practice based on the ADOS-2 and the ADI-R or PARS-TR. Reliability: Reliability of the Japanese version of the TASI (Cronbach's alpha coefficient) | — |
Countries
Japan
Contacts
Public ContactYoshiyuki Tachibana
National Center for Child Health and Development Hospital
Outcome results
None listed