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A prospective cohort study regarding the prognosis, comprehensive geriatric assessment, and health-related QoL in elderly patients with early upper gastrointestinal cancers

A prospective cohort study regarding the prognosis, comprehensive geriatric assessment, and health-related QoL in elderly patients with early upper gastrointestinal cancers - UGIE study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000051734
Enrollment
300
Registered
2023-07-28
Start date
2023-07-28
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients aged 75 years or older with early upper gastrointestinal cancers

Interventions

None listed

Sponsors

Tohoku University Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Patients diagnosed with esophageal/gastric/duodenal tumors by endoscopy (2) Patients diagnosed with cancer by biopsy, or those with tumors strongly suspicious of cancers based on endoscopic findings (3) Patients with esophageal/gastric/duodenal cancers confined to submucosal layer according to endoscopic diagnosis (4) Patients aged 75 years or older (5) Patients with written informed consent for study participation

Exclusion criteria

Exclusion criteria: (1) Patients who refused to participate in this study (2) Patients with esophageal/gastric/duodenal cancers which are suspicious of recurrence (3) Patients who are deemed inappropriate for the study by the investigators

Design outcomes

Primary

MeasureTime frame
Factors related to the prognosis at 3 years after the treatment

Secondary

MeasureTime frame
1. The relationship between impaired HR-QoL and sarcopenia or CGA 2. Factors related to impaired HR-QoL at 3 years after the treatment 3. The relationship between the definite diagnosis of sarcopenia and sarcopenia diagnosed by CT 4. Transition of HR-QoL and CGA 5. Prognosis and factors related to prognosis at 1 year and 5 years after the treatment 6. Prevalence and mortality of other organ cancers detected by CT and factors related to them 7. The relationship between sarcopenia-related genes and sarcopenia at 80 years 8. The relationship between sarcopenia-related genes and prognosis

Countries

Japan

Contacts

Public ContactYohei Ogata

Tohoku University Graduate School of Medicine Division of Gastroenterology

gmaps177@gmail.com022-717-7171

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026