Postoperative patients required mechanical ventilatory support under continuous sedation in the intensive care unit
Conditions
Interventions
During the surgery, the required dose of fentanyl is determined by the individual responsible anesthesiologist. The dose of fentanyl may probably be adjusted within the range of effect-site concentrat
Sponsors
Ehime university
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Postoperative patients required mechanical ventilatory support under a continuous infusion of sedative agents in intensive care until the next morning. The elective surgeries enrolled in this study are as followed, tumor resection and reconstruction by surgeons of otolaryngology or dental surgery or plastic surgery, upper and lower jaw migration by dental surgeons, and thoracoscopic esophageal malignancy surgery.
Exclusion criteria
Exclusion criteria: Patients are 18 years old or less, have severe arrhythmia, atrial fibrillation, and an implanted pacemaker, require high doses of catecholamines, or take some opioid medications preoperatively.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The total dose of remifentanil administered between admission to the intensive care unit and eight hours after admission | — |
Secondary
| Measure | Time frame |
|---|---|
| The mean score of HFVI, the Total dose of sedative agents, the frequency of analgesics required after the termination of mechanical ventilatory support, the VAS score after the termination of mechanical ventilatory support, and the development of delirium after the termination of mechanical ventilatory support | — |
Countries
Japan
Contacts
Public ContactYukihiro Nakasaki
Ehime University Hospital Division of Intensive care unit
Outcome results
None listed