Abdominal Aortic Aneurysm
Conditions
Interventions
Control group: Regular EVAR + IMA embolization for patients with patent inferior mesenteric artery (IMA)
Aneurysmal sac side branch (ASSB) prophylactic embolization group: Regular EVAR + embolization
Sponsors
Nagoya University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients 18 years of age or older with spindle-shaped abdominal aortic aneurysm indicated for surgery (maximum short-axis diameter >50 mm or rapid enlargement >5 mm/6 months) and judged to be eligible for standard EVAR at each institution. Patients who understand the study and give written consent. Patients must be eligible from the date of study approval to March 31, 2026.
Exclusion criteria
Exclusion criteria: Patients whose all lumbar arteries at the aneurysm site are occluded. Subjects with systemic conditions or advanced malignancies that are expected to have a life expectancy of less than 1 year. Patients with known hereditary diseases such as Marfan syndrome or Ehlers-Danlos syndrome Infected aortic aneurysm Isolated iliac artery aneurysm Patients with isolated iliac artery aneurysm, isolated iliac artery aneurysm, cystic aneurysm, or PAU (penetrating atherosclerotic ulcer). Patients with severe allergy to iodine contrast media who cannot use contrast media Patients with renal impairment with preoperative eGFR less than 30 ml/min/1.73 m2 and not on dialysis Women who are pregnant, possibly pregnant, within 28 days postpartum, or lactating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| One-year aneurysm sac shrinkage after EVAR | — |
Secondary
| Measure | Time frame |
|---|---|
| Two- / Three-year sac shrinkage after EVAR, Incidence of type II endoleaks, Overall survival, Freedom from aneurysm-related death, Freedom from re-intervention | — |
Countries
Japan
Contacts
Public ContactYayoi Furuta
Nagoya University Graduate School of Medicine Division of Vascular and Endovascular Surgery, Department of Surgery
Outcome results
None listed