cerebral infarction Transient ischemic attack
Conditions
Interventions
Group with multiple risk factors
group A. Start aspirin 100 mg/day plus prasugrel 3.75 mg/day.
group with few risk factors
designated group B. Initiate aspirin 100 mg/day plus clopidogrel 75 mg/day.
Sponsors
Fujita Health University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients who have given written consent of their own free will after receiving a sufficient explanation before participating in this study. 2. Patients aged 20 years or older at the time of informed consent 3. Patients who are urgently admitted to neurosurgery due to cerebral infarction symptoms or transient ischemic attack
Exclusion criteria
Exclusion criteria: 1. Patients with atrial fibrillation at admission or in the history 2. Cerebral infarction associated with vascular dissection 3. Patients taking concomitant anticoagulants 4. Patients with abnormal platelet count 5. Patients with bleeding such as gastrointestinal bleeding 6. Patients with hypersensitivity to clopidogrel or prasugrel 7. Other patients who are judged to be inappropriate by the principal investigator or co-investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1-2 days, 3-4 days, 1 week, 2 weeks, and 1 month after the start of administration of clopidogrel and prasugrel, respectively. | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of platelet function-suppressing abilities of bayaspirin between both groups within 30 days after drug administration | — |
Countries
Japan
Contacts
Public ContactSaeko Higashiguchi
Fujita Health University Okazaki Medical Center neurosurgery
Outcome results
None listed