Outpatients receiving oral antibiotic prescription
Conditions
Interventions
None listed
Sponsors
Shizuoka Graduate University of Public Health
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: -Cases registered in the Shizuoka Kokuho Database -Patients who received a prescription for oral fluoroquinolones or oral amoxicillin (+/- clavulanic acid) as an outpatient between April 2013 and July 2020 -Patients aged 50 years or older at the time of oral antibiotic prescription -Patients with a baseline period of 1 year prior to oral antibiotic prescription
Exclusion criteria
Exclusion criteria: -Patients who received a prescription for fluoroquinolones or amoxicillin (+/- clavulanic acid) in the 4 months prior to the start of observation (antibiotic prescription episode) -Patients who were hospitalized in the 12 months prior to the start of observation -Cases with history of aortic aneurysm or aortic dissection up to prescription of oral antibiotic (these cases will be analyzed as an additional analysis) -Cases with Marfan syndrome, vascular type Ehlers-Danlos syndrome, and Lois-Dietz syndrome up to prescription of oral antibiotic -Cases that do not allow for a baseline period of 12 months prior to the start of observation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Aortic events (hospitalization due to aortic aneurysm or aortic dissection) from oral antibiotic prescription to 2 months later | — |
Countries
Japan
Contacts
Public ContactChikara Ueki
Shizuoka Graduate University of Public Health Graduate School of Public Health
Outcome results
None listed