Prospective sampling, multicenter study to investigate clinical data and intestinal environment of patients with unexplained abdominal symptoms to explore the association with treatment efficacy and prognosis.

Prospective sampling, multicenter study to investigate clinical data and intestinal environment of patients with unexplained abdominal symptoms to explore the association with treatment efficacy and prognosis. - The study to investigate clinical data and intestinal environment of patients with unexplained abdominal symptoms to explore the association with treatment efficacy and prognosis.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000051617

Enrollment

400

Registered

2023-07-16

Start date

2023-07-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The patients with unexplained abdominal symptoms

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Age: 20 years old or older Gender: any gender Subjects: Patients with unexplained abdominal symptoms and patients without abdominal symptoms

Exclusion criteria

Exclusion criteria: Patients who cannot give their consent to participate in this study. Patients who are unable to collect specimens due to defecation problems.

Design outcomes

Primary

Measure	Time frame
Total bile acid concentration in stool	—

Secondary

Measure	Time frame
Biochemical markers (TP, Alb, AST, ALT, GTP, BUN, Cre, UA, CRP, TG, T-cho, LDL-C, endotoxin, various antibodies, various vitamins, etc.) -Hematological examination (WBC, Hb, Plt, PT, APTT, erythrocyte sedimentation rate, etc.) -Blood metabolome analysis -Hydrogen breath test Lactulose-mannitol test Imaging findings (abdominal x-ray with Schitzmark, abdominal ultrasound, abdominal CT, Cine-MRI, endoscopic findings, etc.) -Pathological findings -Stool metabolome analysis, organic acid analysis -Bile metabolome analysis -Urinary metabolome analysis -Clinical findings, history, complications, and medication history -Questionnaire/Questionnaire -Fecal microbiota analysis	—

Measure

Time frame

Biochemical markers (TP, Alb, AST, ALT, GTP, BUN, Cre, UA, CRP, TG, T-cho, LDL-C, endotoxin, various antibodies, various vitamins, etc.) -Hematological examination (WBC, Hb, Plt, PT, APTT, erythrocyte sedimentation rate, etc.) -Blood metabolome analysis -Hydrogen breath test Lactulose-mannitol test Imaging findings (abdominal x-ray with Schitzmark, abdominal ultrasound, abdominal CT, Cine-MRI, endoscopic findings, etc.) -Pathological findings -Stool metabolome analysis, organic acid analysis -Bile metabolome analysis -Urinary metabolome analysis -Clinical findings, history, complications, and medication history -Questionnaire/Questionnaire -Fecal microbiota analysis

—

Countries

Japan

Contacts

Public ContactTakaomi Kessoku

International university health and welfare Narita hospital Palliative medicine and Gastroenterology

takaomi0027@gmail.com0476355600

Outcome results