Healthy male/female adults
Conditions
Interventions
Ingestion of the test liquid (200 mL) to the subjects within 3 min.
Ingestion of the placebo (200 mL water) to the subjects within 3 min.
Sponsors
CPCC Company Limited
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Healthy male/female subjects ranging in age from 20 to 34, at informed consent. (2) Subjects having less than 25.0 kg/m2 of BMI. (3) Subjects with no smoking (not less than one year). (4) Subjects who can give informed consent to participate in this study, after being provided with an explanation of the protocol detail.
Exclusion criteria
Exclusion criteria: (1) Subjects being under some kind of continuous medical treatment, including the study period. (2) Subjects who have periodically used health-specific / functional/ health foods including supplements, which might affect the autonomic nervous system, metabolism and sleep. (3) Subjects with incompatible chest (e.g., thick bodyhair, pacemaker-fitting) for heartbeat measurements. (4) Subjects with excessive alcohol intake. (5) Subjects with extremely irregular eating habits, and subjects having an irregular life rhythm with irregular shift work or midnight one. (6) At the moment of informed consent, subjects who are under other clinical tests with some kind of medicine/food, or participated in those within four weeks before this study, or are planning to join those after the consent. (7) Subjects who are under a large stress condition with some kind of life event, such as house-moving, transfer, bereavement, etc., within three months before the agreement for this study and during the study period. (8) Subjects with any difficulty in giving up drinking since the day before the scheduled date of this study. (9) Subjects with previous and/or current medical history of serious diseases in heart, liver, kidney and/or digestive organs. (10) Subjects getting excessive exercise every day. (11) Subjects with a serious symptom of premenstrual syndrome. (12) Subjects who will be determined as the condition of being over-sensitiveness to cold, judging from the investigator's opinion at informed consent. (13) Pregnant, possibly pregnant, and lactating women. (14) Subjects having some kind of drug and/or food allergy. (15) Subjects who break out in a rash from putting electrodes on the head and chest. (16) Subjects with an external injury on their right forefinger. (17) Others who have been determined as ineligible for participation, judging from the principal/sub investigator's opinions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitrax (symbol-digit coding, stroop, and shifting attention) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The Profile of Mood States Second Edition (Japanese short ver.) 2. Psychological questionnaire 3. Heartbeat | — |
Countries
Japan
Contacts
Public ContactMasanori Numa
CPCC Company Limited Clinical Planning Department
Outcome results
None listed