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The impact of reducing specific blue light on melatonin and sleep quality: a randomized controlled trial

The correlation between the reduction of short-wavelength light exposure, which inhibits bedtime melatonin production, and its effects on sleep, autonomic nervous function, stress hormones, and oxidative stress: a randomized controlled trial - The correlation between the reduction of short-wavelength light exposure, which inhibits bedtime melatonin production, and its effects on sleep, autonomic nervous function, stress hormones, and oxidative stress: a randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000051560
Enrollment
50
Registered
2023-07-09
Start date
2023-12-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non-functioning endocrine disease

Interventions

The glasses that selectively reduce short-wavelength light with a similar absorbance sensitivity to ipRGCs (referred to as &quot
reducing glasses&quot
) and glasses that have minimal reduction effects but are difficult to distinguish from the reducing glasses based on appearance (referred to as &quot
non-reducing glasses&quot
) will be transferred to our university in a randomly packaged state by Mitsui Chemicals. Upon admission, the principal investigator or collaborator will distribute one of the packaged glasses to e

Sponsors

Hyogo Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Participants who meet all of the following criteria will be included in the study: 1. Patients who have risk factors of atherosclerosis. 2. Individuals who have received sufficient explanations about participation in the study, have a thorough understanding, and have provided written consent voluntarily. 3. Excluding those deemed inappropriate as research subjects by the principal investigator, and all other criteria have been met.

Exclusion criteria

Exclusion criteria: Individuals who do not meet the eligibility criteria.

Design outcomes

Primary

MeasureTime frame
Melatonin, 6-sulphatoxymelatonin, and physical activity and autonomic nervous function during sleeping time

Secondary

MeasureTime frame
d-ROM, urine cortisol

Countries

Japan

Contacts

Public ContactAkinori Kanzaki

Hyogo Medical University Diabetes, Endocrinology, and Clinical immunology

akanzaki@hyo-med.ac.jp0798-45-6473

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026