Breast cancer
Conditions
Interventions
Mild hypofractionated postoperative radiation therapy 42.56 Gy in 16 daily fractionations for patients with high-risk breast cancer.
Sponsors
Hyogo Cancer Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Postoperative breast cancer patients who meet the indication criteria for adjuvant radiation therapy including chest wall/conserved breast and regional lymph node in Hyogo Cancer Center Breast Cancer Guidelines.
Exclusion criteria
Exclusion criteria: Patients with malignancy other than breast cancer, infective disease requiring systemic therapy, fever (> 100 F), diabetes mellitus (HbA1c => 7.0 %), lung fibrosis/interstitial lung disease/severe emphysema, active collagen vascular disease, or genetic disorders high-risk for radiation. Patients who are (possibly) pregnant, breast feeding, receiving systemic steroids or immune-suppression therapy, planned to have breast reconstruction surgery, unable to raise her/his arms above shoulders, or receiving radiation therapy including internal mammary node region.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acute or subacute adverse events of CTACE grade 2+ occurring within 6 months from radiation therapy completion | — |
Countries
Japan
Contacts
Public ContactHaruka Uezono
Hyogo Cancer Center Department of Radiation Oncology
Outcome results
None listed