Frail elderly subjects
Conditions
Interventions
octanoate group"
that takes MCT (C8:0). C8:0 Mix 6 g (54 kcal) of MCT containing about 97% with rice or miso soup and take it for lunch. The intervention will last approximately 1.5 months.
The second group is the &qu
decanoic acid group"
taking MCT (C10:0). C10:0 Mix 6 g (54 kcal) of MCT containing about 97% with rice or miso soup and take it for lunch. The intervention will last approximately 1.5 months.
The third group is the "
LCT group,"
that takes LCT. LCT is mixed with rice or miso soup and consumed for lunch. The intervention will last approximately 1.5 months.
Sponsors
Tezukayama University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Elderly subjects in a nursing care home for the elderly volunteered to participate in a 3-mo dietary supplement intervention program. All residents in this nursing care home need special care by other people for living. They are classified into Japanese nursing care levels with number between 1 and 5 based on assessed care needs.
Exclusion criteria
Exclusion criteria: Those in need of enteral or intravenous nutritional therapy. Patients who have severe dysphagia and cannot take food orally. Those who have a level of consciousness rating (JCS: Japan coma scale) of 2-2 or higher. Type I diabetes mellitus and those with serious cardiac, hepatic, renal, or hematological diseases. Fasting blood glucose level of 200 mg/dl or higher. CRP 2.0 mg/dl or higher. Persons who frequently fall ill. BMI 25.0 kg/m2 or higher. Subjects with relevant food allergies. Persons who are unable to understand the study. Persons who are judged not to be included in the study by the facility director, who is the facility physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in physical function, cognitive function, and swallowing function will be compared before and after 1.5 months of intervention. Body measurements and body composition will be estimated by body weight, body mass index (BMI), body fat percentage, body fat mass, skeletal muscle mass, upper arm circumference (AC), triceps subcutaneous fat thickness (TSF), upper arm muscle circumference (AMC), upper arm muscle area (AMA), and lower leg circumference (CC). Physical performance is estimated by grip strength, maximum walking speed, number of repetitive openings and closings of the lower extremities, quadriceps endurance, lower extremity muscle strength, respiratory muscle function (peak flow meter), and functional independence measures (FIM). Cognitive function is estimated with the Mini-Mental State Examination (MMSE) and the N Mental State Rating Scale for the Elderly (NM scale). Eating and swallowing function is estimated with the Repeated Saliva Swallowing Test (RSST), the Revised Water Swallowing Test (MWST), and tongue pressure muscle strength. | — |
Countries
Japan
Contacts
Public ContactSakiko Abe
Tezukayama University Department of Food and Nutrition, Faculty of Contemporary Human Life Science
Outcome results
None listed