Adult
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) A healthy Japanese females aged 60-69 at the time of consent. 2) Subjects can understand and comply with the rules written in protocol during clinical study period. 3) Subjects whose written informed consent has been obtained.
Exclusion criteria
Exclusion criteria: The following exclusion criteria apply to subjects. 1) Routinely use cosmetics that claim to have an effect on the skin microbiota. 2) With a preexsiting or current condition of skin allergies. 3) Attend a dermatologist or cosmetic dermatologist for skin diseases on the scalp or face. (including those being treated for atopic dermatitis, seborrheic dermatitis, contact dermatitis, psoriasis, athlete's foot on the scalp, etc.) 4) With trauma or inflammation of the scalp or face. 5) Receiving hormone replacement therapy. (estrogen, progesterone preparations (oral, paste, ointment, etc.)) 6) Have got cosmetic surgery which would affect the measuring area within 1 year. 7) Have got special treatment within 1 month. (facial esthetics, epilation etc.) 8) Have an irregular habit because of working at night or working under work-shift form. 9) Drink more than 500 mL of beer equivalent daily. 10) Have been smoking (including electronic cigarettes) for 3 months prior to obtaining consent. 11) Participated in other clinical trial within 1 month. 12) Working at the health food, cosmetics or pharmaceutical company. 13) Deemed inappropriate to participate in this study by the principle investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin microbiota Water content of stratum corneum Transepidermal water loss Sebum pH Image analysis of facial skin Skin questionnaire | — |
Countries
Japan
Contacts
Yamada Bee Company, Inc. Yamada Bee Company group Institute for Beauty Science, R&D department