Familial adenomatous polyposis
Conditions
Interventions
None listed
Sponsors
Department of Gastrointestinal Oncology, Osaka International Cancer Institute
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients diagnosed with familial adenomatous polyposis and undergoing or scheduled to undergo IDP 2) Those who have not undergo colectomy, or those who had undergone colectomy and had 10 cm or more of large intestine remaining 3) Patients aged 18 to 80 years old 4) Patients with ECOG PS 0 or 1 5) Patients with written informed consent
Exclusion criteria
Exclusion criteria: 1) Patients known to have colorectal lesion larger than 15 mm 2) Those who had dense polyps 3) Patients with serious other organ disease 4) Patients continuing antithrombotic drugs, for whom IDP should not be carried out according to the Japanese guidelines 5) Patients continuing systemic administration of steroid 6) Patients receiving anticancer agents 7) Those who have psychosis or psychiatric symptoms that would make participation in the study difficult 8) Patients with active infection disease 9) Patients deemed by the investigator to be inappropriate to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of severe adverse events (delayed bleeding and perforation) | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse events related to IDP, procedure time, degree of abdominal pain on the day following IDP, presence of hematochezia after IDP, emergency colonoscopy and readmission to the hospital | — |
Countries
Japan
Contacts
Public ContactYasuhiro Tani
Osaka International Cancer Institute Department of Gastrointestinal Oncology
Outcome results
None listed