Exploration of prevention and treatment of vascular cognitive impairment in patients with asymptomatic carotid artery stenosis/occlusion

Exploration of prevention and treatment of vascular cognitive impairment in patients with asymptomatic carotid artery stenosis/occlusion - Exploration of prevention and treatment of vascular cognitive impairment in patients with asymptomatic carotid artery stenosis/occlusion

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000051392

Enrollment

Registered

2023-06-20

Start date

2021-02-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asymptomatic carotid artery stenosis/occlusion

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The inclusion criteria of patients who visited NCVC between July 2020 and March 2025 were as follows: (i) Patients with asymptomatic CASO who showed a peak systolic velocity of>130 cm/s at a stenotic lesion or occlusion identified by carotid Doppler ultrasonography.(ii) Patients who underwent neuropsychological examinations including Montreal Cognitive Assessment (MoCA) and Alzheimer's Disease Assessment Scale-Cognitive Subscale 13 (ADAS-Cog). (iii) Patients who underwent also 15O-gas PET.

Exclusion criteria

Exclusion criteria: Patients deemed by the investigator to be ineligible for participation in this study.

Design outcomes

Primary

Measure	Time frame
Preservation/improvement of cognitive function in patients with asymptomatic carotid artery stenosis/occlusion	—

Countries

Japan

Contacts

Public ContactYorito Hattori

National Cerebral and Cardiovascular Center Department of Neurology

yoh2019@ncvc.go.jp06-6170-1070

Outcome results