Prediction for elevation value of platelet count in the blood and plasma concentration of fibrinogen following transfusion of platelet products and fresh frozen plasma during modifed ultrafiltration in cardiac surgeries for neonates and infants

Prediction for elevation value of platelet count in the blood and plasma concentration of fibrinogen following transfusion of platelet products and fresh frozen plasma during modifed ultrafiltration in cardiac surgeries for neonates and infants - Elevation value of platelet count and fibrinogen concentration following transfusion of platelet products and fresh frozen plasma during modifed ultrafiltration in pediatric patients

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000051347

Enrollment

Registered

2023-06-15

Start date

2023-06-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital Heart Disease

Interventions

Transfusion of platelets of 0 - 200 ml and fresh frozen plasma of 0 - 300 ml with elimination of excess water during modified ultrafiltration following cesssation of the cardiopulmonary bypass.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) infants and neonates undergoing cardiac surgeries with cardiopulmonary bypass in our institution And 2) written informed consent is obtained from a parent of each patient.

Exclusion criteria

Exclusion criteria: 1) cases of written informed consent not obtained from the parent of the patient Or 2) cases of modified ultrafiltration not performed following cessation of the cardiopoumonary bypass Or 3) cases of modified ultrafiltration interrupted with second pump run

Design outcomes

Primary

Measure	Time frame
1) arterial blood gas, platelet count, and plasma concentration of fibrinogen at cessation of transfusion of plateles and fresh frozen plasma during MUF	—

Secondary

Measure	Time frame
2) fibrinogen concentration in the blood at cessation of transfusion of fresh frozen plasma during MUF 3) blood loss and the total amount of transfusion follwing cessation of the cardiopulmonary bypass 4) arterial blood gas, platelet count, and plasma concentration of fibrinogen on the time point of admission in the postoperative care unit	—

Countries

Japan

Contacts

Public ContactTatsuhiko Masue

Gifu Prefectural General Medical Center Department of Anesthesiology

tatsuhikomasue@yahoo.co.jp+81-58-246-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026