The usefulness of multiparametric ultrasound for the assessment of patients with autoimmune hepatitis

The usefulness of multiparametric ultrasound for the assessment of patients with autoimmune hepatitis - AIH study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000051252

Enrollment

100

Registered

2023-06-03

Start date

2023-05-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autoimmune hepatitis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients who are suspected to have Autoimmune Hepatitis (AIH) and are scheduled for liver biopsy 2) Patients from whom other diseases have been excluded (such as alcohol, drugs, viral infections, metabolic diseases, cases with PBC) 3) Men and women aged 20 and above

Exclusion criteria

Exclusion criteria: 1) Patients who the principal investigator or co-investigator has deemed unsuitable for this study.

Design outcomes

Primary

Measure	Time frame
The correlation between ultrasonic parameters (LS, DS, AC) and pathological parameters (fibrosis, lobular inflammation, steatosis).	—

Secondary

Measure	Time frame
1.Diagnostic capability of liver fibrosis by LS (F0 vs. F1234, F01 vs. F234, F012 vs. F34, F0123 vs. F4) 2.Diagnostic capability of lobular inflammation by DS (A0 vs. A123, A01 vs. A23, A012 vs. A3) 3.Diagnostic capability of liver steatosis by AC (S0 vs. S123, S01 vs. S23, S012 vs. S3) 4.Progression of ultrasound parameters before treatment and 3, 6, 9, 12 months after treatment initiation. 5.The impact of subcutaneous thickness on ultrasound parameters (LS, DS, AC).	—

Measure

Time frame

1.Diagnostic capability of liver fibrosis by LS (F0 vs. F1234, F01 vs. F234, F012 vs. F34, F0123 vs. F4) 2.Diagnostic capability of lobular inflammation by DS (A0 vs. A123, A01 vs. A23, A012 vs. A3) 3.Diagnostic capability of liver steatosis by AC (S0 vs. S123, S01 vs. S23, S012 vs. S3) 4.Progression of ultrasound parameters before treatment and 3, 6, 9, 12 months after treatment initiation. 5.The impact of subcutaneous thickness on ultrasound parameters (LS, DS, AC).

—

Countries

Japan

Contacts

Public ContactKatsutoshi Sugimoto

Tokyo Medical University Hospital Dept of Gastroenterology and Hepatology

sugimoto@tokyo-med.ac.jp03-3342-6111

Outcome results