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Exploratory clinical research to establish a novel method for measuring liver function using a fluorescence spectrometer

Exploratory clinical research to establish a novel method for measuring liver function using a fluorescence spectrometer - Fluorence spectrometer liver function

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000051209
Enrollment
8
Registered
2023-05-31
Start date
2024-01-09
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholecystlithialsis Gastric tumor Pancreatic tumor Biliary tumor

Interventions

None listed

Sponsors

Hokkaido University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Persons who are 20 years of age or older at the time of obtaining consent. (2) Persons who have received a full explanation of their participation in this research and who have given the consent of their own free will based on a thorough understanding of the subject's situation.

Exclusion criteria

Exclusion criteria: Patients with any one of the following conditions shall be excluded (i) Patients with a history of hepatectomy or common bile duct resection (2) Patients with a history of allergy to Dianogreen (iii) Patients with known dianogreen excretion disorder (iv) Patients with a history of iodine allergy (5) Patients with a history of upper abdominal surgery (vi) Patients who have received anti-tumour therapy (chemotherapy or radiation therapy) within six months prior to the surgery (vii) Other subjects deemed inappropriate as research subjects by the principal investigator or sub-investigator.

Design outcomes

Primary

MeasureTime frame
The correlation coefficient between fluorescence intensity on the liver surface obtained by Lumifinder and ICG regression rate.

Secondary

MeasureTime frame
(1) Correlation between fluorescence intensity change rate in left and right lobes of liver (2) Correlation between ICGK in blood and the rate of change of fluorescence intensity (3) Correlation between measurement results of other modalities and rate of change of fluorescence intensity on the liver surface (iv) Correlation between the rate of change of fluorescence intensity and the results of blood biochemical tests (AT-III, total bilirubin level, liver enzymes, and biliary enzymes) after hepatectomy.

Countries

Japan

Contacts

Public ContactTakehiro Noji

Hokkaido University Faculty of Medicine Gastroenterological surgery II

drnoji@med.hokudai.ac.jp0117067714

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026