Effect of propofol on salivary secretion from the submandibular, sublingual, and labial glands during intravenous sedation.

Effect of propofol on salivary secretion from the submandibular, sublingual, and labial glands during intravenous sedation. - Effect of propofol on salivary secretion from the submandibular, sublingual, and labial glands during intravenous sedation.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000051146

Enrollment

Registered

2023-05-23

Start date

2017-06-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental phobia

Interventions

An intravenous catheter was inserted into the median cubital vein, and lactated Ringer&#39

s solution was infused at 2 mL/kg/h. The participants were placed in a sitting position on a dental chair for 20 min. After confirming that the cardiovascular parameters were in a steady state, the pa

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Participants were categorized according to the American Society of Anesthesiologists physical status 1,

Exclusion criteria

Exclusion criteria: Exclusion criteria was subject except for Anesthesiologists physical status 1.

Design outcomes

Primary

Measure	Time frame
Salivary flow rates in the submandibular, sublingual glands, and the labial glands	—

Secondary

Measure	Time frame
Mean blood pressure, pulse rate, and sedation level Amylase activity in the saliva from the submandibular and sublingual glands	—

Countries

Japan

Contacts

Public ContactHiroyoshi Kawaai

Ohu University School of Dentistry Department of Oral Function and Molecular Biology

maromaro@ce.mbn.or.jp0249329337

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026