Diabetes, Sarcopenia
Conditions
Interventions
Implement nutritional dietary guidance on protein intake. Specifically, protein-enriched food (commercially available) will be provided, and the daily protein intake will be 1.5 g or more per 1 kg of
Sponsors
Kansai Electric Power Medical Research Institute
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Diabetic patients aged 65 and over (2) Subjects with decreased muscle mass or grip strength (SMI: men <7.0 kg/m^2, women <5.7 kg/m^2, grip strength: men <28 kg, women <18 kg) (3) Subjects whose protein intake is less than 1.2g/kg/day (4) Patients who are outpatients (5) Persons who can write dietary records
Exclusion criteria
Exclusion criteria: (1) Subjects with obvious dementia or mental illness (2) Persons using steroids (3) Patients with liver disorder with Child Pugh classification of 7 points or more, or renal dysfunction with eGFR less than 45 (4) Heart failure with limitation of physical activity (New York Heart Association classification of heart failure II or higher) (5) Subjects who have a history of gastrointestinal reconstructive surgery (6) Subjects who have incurable cancer (7) Those who have a cardiac pacemaker or an implanted cardioverter-defibrillator (8) Subjects with motor paralysis in the extremities due to central neuromuscular disease (9) Persons who are judged to be inappropriate for this clinical study by the research implementation supervisor or co-investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in muscle mass, grip strength, and breakfast protein intake ratio over 6 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in stratum corneum water content, physical activity, and blood biochemical tests (HbA1c, creatinine, estimated glomerular filtration rate) over a 6 months. | — |
Countries
Japan
Contacts
Public ContactShota Moyama
Kansai Electric Power Medical Research Institute Department of Metabolism and Nutrition, Diabetes Research Center
Outcome results
None listed