Prospective observational study of plasma cortisol levels and postoperative circulatory failure and organ damage in cardiac major vascular surgery underl cardiopulmonary bypass

Prospective observational study of plasma cortisol levels and postoperative circulatory failure and organ damage in cardiac major vascular surgery underl cardiopulmonary bypass - Prospective observational study of plasma cortisol levels and postoperative circulatory failure and organ damage in cardiac major vascular surgery underl cardiopulmonary bypass

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000051094

Enrollment

300

Registered

2023-05-18

Start date

2023-05-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular disease requiring surgery under cardiopulmonary bypass

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Heart disease (valvular disease, coronary artery disease, short circuit, tumor, endocarditis, pericarditis, vascular disease)

Exclusion criteria

Exclusion criteria: Case of extracorporeal membrane oxygenation theapy

Design outcomes

Primary

Measure	Time frame
Plasma cortisol level, VIS score, SOFA score	—

Secondary

Measure	Time frame
28-day mortality, Ventilator time, ICU length of stay, Arrhythmia, Acute renal failure, Tracheostomy, Infection, Biomarkers (I-FABP, IL-6, procalcitonin, endotoxin activity)	—

Countries

Japan

Contacts

Public ContactNaoya Iwasaki

Nagasaki university graduate school of biomedical sciences department of anesthesiology and intensive care medicine

n-iwasaki@nagasaki-u.ac.jp095-819-7370

Outcome results