Efficacy of biomarkers for predicting relapse in patients with ulcerative colitis with clinical remission: A single-center prospective study

Efficacy of biomarkers for predicting relapse in patients with ulcerative colitis with clinical remission: A single-center prospective study - Efficacy of biomarkers for predicting relapse in patients with ulcerative colitis with clinical remission: A single-center prospective study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000050963

Enrollment

Registered

2023-05-20

Start date

2023-05-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ulcerative Colitis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients who met the criteria for ulcerative colitis 2) Patients over 18 years old 3) Patients with clinical remission (Partial Mayo score under 2) over 3 months 4) In combination therapy, patients on a constant dose before this study participation as follows: (a)5-aminosalicylic acid over 4 weeks (b)immunomodulators over 4 weeks (c)biologics over 8 weeks 5) Patients who have contents for this study

Exclusion criteria

Exclusion criteria: 1) Patients who are hospitalized 2) Patients with colostomy 3) Patients who are pregnant or may become pregnant 4) Patients who smoke 5) Patients with other inflammatory diseases 6) Patients receiving the following treatments within 4 weeks (a)NSAIDs (b)Aspirin (c)Budesonide rectal foam and enemas (d)Corticosteroids (e)Cytapheresis 7) Patients with malignant tumors (except after resection or remission) 8) Patients judged to be inappropriate for inclusion in this study

Design outcomes

Primary

Measure	Time frame
The sensitivity and specificity of biomarkers for clinical relapse in patients with ulcerative colitis with clinical remission.	—

Countries

Japan

Contacts

Public ContactNaohiro Kato

National Hospital Organization Kure Medical Center and Chugoku Cancer Center Department of Gastroenterology

kato.naohiro.zy@mail.hosp.go.jp0823-22-3111

Outcome results