Schizophrenia
Conditions
Interventions
Intervention: Cognitive remedial therapy (NEAR) + exercise therapy (aerobic exercise) + usual treatment group
Control: Cognitive remedial therapy (NEAR) + usual treatment group
Sponsors
Department of Psychiatry, Tohoku University Hospital Department of Psychiatry, Graduate School of Medicine, Tohoku University
Miyagi Psychiatric Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Patients with schizophrenia who are outpatients at Tohoku University Hospital Psychiatry Department and Miyagi Psychiatric Medical Center (2) Subjects who have been successfully treated with drugs and judged by the attending psychiatrist to be in a state of no significant hallucinations or delusions. Any stage is acceptable. (3) Age between 20 and 40 (at the time of registration). IQ>70 (4) Regardless of gender (5)Patients who have given their voluntary written consent after receiving a sufficient explanation for participating in this study. (6) Patients who are already registered with daycare in both hospitals or who are considering registration with daycare and who are judged by attending psychiatrists to require treatment at daycare.
Exclusion criteria
Exclusion criteria: (1) Those who have a medical history or undergoing treatment at the time of first registration as follows; substance dependence, head injury, lifestyle-related diseases (hypertension, hyperlipidemia, diabetes), or vascular disorders (brain, cardiac, etc.), eye disease (cataract, glaucoma, etc.) or severe visual impairment (myopia, hyperopia, etc.), diagnosis of dementia, or those who score 21 points or less on the cognitive function evaluation MMSE (Mini-Mental State Examination). (2) Subjects whose exercise is restricted by a doctor for some reason (orthopedic or medical reasons) at the time of first registration. (3)Patients judged by the attending psychiatrist to be significantly lacking in consent due to marked hallucinations/delusions or thought disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| (1) Evaluation of neurocognitive/social cognition function: The Brief Assessment of Cognition in Schizophrenia Japanese version (BACS.J), Social Cognition Screening Questionnaire Japanese version (SCSQ.J) (2) Psychiatric symptoms assessment: Global Assessment of Functioning (GAF), Positive and Negative Syndrome Scale (PANSS) (3) Evaluation of quality of life (QOL): Schizophrenia Quality of Life Scale Japanese version (SQLS.J) (4) Retinal layers: Measure the retinal nerve fiber layer (RNFL), ganglion cell layer complex (GCC), macular volume, macular thickness, etc by SD-OCT. Implemented only at Tohoku University Hospital. (5) Evaluation of Body composition: body fat percentage, muscle mass, basal metabolic rate, etc. (measured by body composition meter) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Evaluation of self-stigma: The Internalized Stigma of Illness Scale, Japanese version (ISMI.J) 2) Evaluation of personality tendency: Ten Item Personality Inventory Japanese versions (TIPI.J), The Autism-Spectrum Quotient Japanese versions (AQ.J) | — |
Countries
Japan
Contacts
Public ContactHiroshi Komatsu
Tohoku University Hospital Department of Psychiatry
Outcome results
None listed