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Daily use of Duloxetine is effective in treating premature ejaculation: A prospective randomized placebo-controlled crossover clinical trial

Daily use of Duloxetine is effective in treating premature ejaculation: A prospective randomized placebo-controlled crossover clinical trial - Daily use of Duloxetine is effective in treating premature ejaculation: A prospective randomized placebo-controlled crossover clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000050874
Enrollment
100
Registered
2023-04-19
Start date
2022-05-17
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

male sexual function

Interventions

34 patients will receive duloxetine then placebo in group A 34 patients will receive placebo then duloxetine in group B

Sponsors

Kasr AlAiny faculty of medicine
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: Male patients with PE (primary or secondary) with stable and committed relationship having (IELT) < 2 minutes were included

Exclusion criteria

Exclusion criteria: Patients with erectile dysfunction (ED), reduced sexual desire or inhibited male orgasm or active genitourinary tract infection (confirmed by two glasses of urine and EPS) or known mental disorders (Depression, Anxiety, Schizophrenia) or uncontrolled physical illnesses (Hepatic, Renal, Cardiac, Neurological, Endocrinal) were excluded from the study. Finally, any alcohol or drug abuser or patient with known hypersensitivity to duloxetine was excluded from the study.

Design outcomes

Primary

MeasureTime frame
improvement in premature ejaculation

Secondary

MeasureTime frame
impact on sexual function and quality of life

Countries

Africa

Contacts

Public Contactsameh gamalel din

Kasr AlAiny faculty of medicine Andrology & STDs

samehfayek@hotmail.com01227109309

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026