Hemodynamic study of the portal venous region using 3D cine phase contrast MRI (4D Flow MRI)

Hemodynamic study of the portal venous region using 3D cine phase contrast MRI (4D Flow MRI) - Hemodynamic study of the portal venous region using 3D cine phase contrast MRI (4D Flow MRI)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000050870

Enrollment

250

Registered

2023-05-15

Start date

2023-07-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

abnormal portal venous hemodynamics

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients requiring evaluation of blood flow in the portal venous region. Specifically, patients with hepatic dysfunction or patients who require evaluation before and after treatment. Adult patients who understand the study and have given written consent.

Exclusion criteria

Exclusion criteria: Patients who have difficulty with MRI imaging, such as claustrophobia or implantation of non-MRI compatible metal devices. For contrast studies, patients with contrast allergy or renal insufficiency.

Design outcomes

Primary

Measure	Time frame
For liver transplant donors and recipients, liver volume increase at 3 months postoperatively (increased portal venous blood flow/wall shear stress postoperatively as an exposure/predictor); for cases of portal vein thrombus (RRT value of the main trunk of the portal vein as an exposure/predictor); and for hepatic encephalopathy, improvement of hepatic encephalopathy after transcatheter portal collateral embolization (increased liver blood flow and changes in blood flow from the superior mesenteric vein into the portal vein due to portosystemic shunt embolization as exposure/predictor) will be evaluated.	—

Measure

Time frame

For liver transplant donors and recipients, liver volume increase at 3 months postoperatively (increased portal venous blood flow/wall shear stress postoperatively as an exposure/predictor); for cases of portal vein thrombus (RRT value of the main trunk of the portal vein as an exposure/predictor); and for hepatic encephalopathy, improvement of hepatic encephalopathy after transcatheter portal collateral embolization (increased liver blood flow and changes in blood flow from the superior mesenteric vein into the portal vein due to portosystemic shunt embolization as exposure/predictor) will be evaluated.

—

Countries

Japan

Contacts

Public ContactRyota Hyodo

Nagoya University Hospital Radiology

ryouta771@med.nagoya-u.ac.jp0527442327

Outcome results