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Prefrontal Cortex Activity During Real-time Walking in Acute Stroke: Effects of Walking and Cognitive Function

Prefrontal Cortex Activity During Real-time Walking in Acute Stroke: Effects of Walking and Cognitive Function - Prefrontal Cortex Activity During Real-time Walking in Acute Stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000050859
Enrollment
54
Registered
2023-04-16
Start date
2023-05-08
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute stroke

Interventions

None listed

Sponsors

Kobe City Medical Center General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Acute stroke patients 1. Patients undergoing rehabilitation intervention at Kobe City Medical Center General Hospital 2. Patients whose physicians decide to start weaning based on clinical criteria 3. Patients who are 20 years of age or older 4. Patients who do not require walking assistance (FIM-walk >= 6) 5. Patients who were ambulatory and independent in the community before the onset of illness. 6. First stroke 7. Patients who meet the criteria 1-6 and whose consent to participate in the study was obtained during hospitalization. healthy elderly 1. who live in the community 2. who self-report as healthy 3. who are at least 20 years of age 4. who have obtained consent to participate in the research

Exclusion criteria

Exclusion criteria: Acute stroke patients 1. patients with cognitive impairment (MMSE < 21) 2. patients with neurological diseases other than post-stroke sequelae 3. patients with uncontrolled hypertension 4. patients with leg pain to the extent that it interferes with walking 5. patients with severe obesity (BMI > 40) 6. congestive heart failure, severe valvular disease, history of cardiac arrest, presence of an implantable cardioverter-defibrillator, uncontrolled angina or other macrovascular disease, and history of myocardial infarction or cardiac surgery within 1 year 7. patients on corticosteroids 8. patients with respiratory disease requiring oxygen therapy 9. Patients with renal disease requiring dialysis 10. patients with significant visual or vestibular disturbances that affect safe ambulation 11. patients with lower motor neuron impairment 12. patients with fractures or artifacts within 6 months 12. patients who have had a fracture or joint replacement within the past 6 months 13. patients with terminal cancer 14. patients who are deemed inappropriate for participation in the study by the principal investigator or study investigators. healthy elderly 1. with cognitive impairment (MMSE < 21) 2. with neurological disease 3. with mental illness 4. who have a disease that affects mobility

Design outcomes

Primary

MeasureTime frame
oxyhemoglobin concentration in the prefrontal cortex during each task will be measured using functional near infrared spectroscopy in acute stroke patients within 14 days of onset and healthy elderly subjects.

Countries

Japan

Contacts

Public ContactTomoya Takahashi

Kobe City Medical Center General Hospital Rehabilitation Technology Department

tomjpn99@gmail.com078-302-4321

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026