Follow up study of patients undergoing catheter ablation for atrial fibrillation:evaluation of long-term outcomes and predictive factors based on genetic predisposition-subgroup analysis in patients with atrial biopsy and proteomics

Follow up study of patients undergoing catheter ablation for atrial fibrillation:evaluation of long-term outcomes and predictive factors based on genetic predisposition-subgroup analysis in patients with atrial biopsy and proteomics - FUTURE-AF-S Study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000050841

Enrollment

300

Registered

2023-04-13

Start date

2022-07-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrial fibrillation

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1)Patients who have agreed to participate in the FUTURE-AF study (2)Patients who undergo radiofrequency catheter ablation for atrial fibrillation during the period from the approval of the ethical review of clinical research to December 31, 2026. (3)Age 18 years or older

Exclusion criteria

Exclusion criteria: (1)Patients who are judged by the attending physician to be unsuitable for participation in the study (2)Patients who have expressed their non-participation in the study

Design outcomes

Primary

Measure	Time frame
Association of genetic markers or genetic risk scores with histological findings and proteomic data	—

Secondary

Measure	Time frame
Association of histological findings with proteomic data Association of histological findings with transcriptomic data Association of proteomic data with transcriptomic data Association of histological findings with 3-year post-ablation outcomes Association of proteomic data with 3-year post-ablation outcomes Association of transcriptomic data with 3-year post-ablation outcomes Association of histological findings with cardiovascular events Association of proteomic data with cardiovascular events Association of transcriptomic data with cardiovascular events Association of histological findings with atrial tachyarrhythmia recurrence Association of proteomic data with atrial tachyarrhythmia recurrence Association of transcriptomic data with atrial tachyarrhythmia recurrence	—

Measure

Time frame

Association of histological findings with proteomic data Association of histological findings with transcriptomic data Association of proteomic data with transcriptomic data Association of histological findings with 3-year post-ablation outcomes Association of proteomic data with 3-year post-ablation outcomes Association of transcriptomic data with 3-year post-ablation outcomes Association of histological findings with cardiovascular events Association of proteomic data with cardiovascular events Association of transcriptomic data with cardiovascular events Association of histological findings with atrial tachyarrhythmia recurrence Association of proteomic data with atrial tachyarrhythmia recurrence Association of transcriptomic data with atrial tachyarrhythmia recurrence

—

Countries

Japan

Contacts

Public ContactTAKANORI YAMAGUCHI

Saga University Hospital Department of Cardiovascular Medicine

takanori@cc.saga-u.ac.jp0952342443

Outcome results