Can perioperative change in serum markers of oxidative stress predict acute exacerbation of interstitial lung disease in lung cancer patients undergoing surgical resection?

Perioperative change in serum markers of oxidative stress in lung cancer patients with interstitial lung disease undergoing surgical resection. - Perioperative change in oxidative stress in patients with interstitial lung disease undergoing surgical resection.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000050816

Enrollment

Registered

2023-04-11

Start date

2024-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer patients with interstitial lung disease undergoing surgical resection

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Primary lung cancer or Suspicion of primary lung cancer 2. 18 y.o. or older 3. ECOG performance status:0-1 4. No previous history of lung resection 5: Radiological usual interstitial pneumonia (UIP) pattern and possible UIP pattern on an Official ATS/ERS/JRS/ALAT Clinical Practice Guideline 6. Written informed consent is obtained

Exclusion criteria

Exclusion criteria: 1. Inconsistent with UIP pattern on an Official ATS/ERS/JRS/ALAT Clinical Practice Guideline 2. Considered inappropriate by attending physician

Design outcomes

Primary

Measure	Time frame
The association between perioperative change in serum levels of Diacron-reactive oxygen metabolites and Biological antioxidant potential, and the incidence of postoperative acute exacerbation of interstitial lung disease	—

Countries

Japan

Contacts

Public ContactTerumoto Koike

Niigata University Graduate School of Medical and Dental Sciences Thoracic and Cardiovascular Surgery

t-koike@med.niigata-u.ac.jp025-227-2243

Outcome results