Effects of compression therapy on orthostatic blood pressure regulation in healthy adults

Hemodynamic mechanisms underlying the change in orthostatic systolic blood pressure with compression - Hemodynamic mechanisms underlying the change in orthostatic systolic blood pressure with compression

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000050807

Enrollment

Registered

2023-04-10

Start date

2023-04-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Abdominal compression during the head-up tilt testing: an inflatable abdominal bandage is applied with a pressure of 40+/-5 mmHg -&gt

10-min washout period -&gt

No compression during the head-up tilt testing No compression during the head-up tilt testing -&gt

Abdominal compression during the head-up tilt testing: an inflatable abdominal bandage is applied with a pressure of 40+/-5 mmHg

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Individuals with no smoking habit 2. Individuals who agree to participate in this study

Exclusion criteria

Exclusion criteria: 1. Individuals who have a limited range of motion and/or pain that prevent them to perform a head-up tilt test 2. Individuals who cannot undergo compression therapy due to skin symptoms, such as itching and pain 3. Individuals who are or may be pregnant 4. Individuals who have cardiac and peripheral circulatory diseases 5. Individuals who are taking any autonomic drug such as antihypertensive medications and bronchodilators 6. Individuals who have implanted metal devices

Design outcomes

Primary

Measure	Time frame
Systolic blood pressure	—

Secondary

Measure	Time frame
Heart rate, stroke volume, cardiac output, total peripheral resistance, heart rate variability parameters, baroreflex sensitivity, skeletal muscle mass index, hydration	—

Countries

Japan

Contacts

Public ContactKazuaki Oyake

Shinshu University Department of Physical Therapy

k_oyake@shinshu-u.ac.jp0263372413

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026