Healthy adult
Conditions
Interventions
Capsules containing 762 mg propolis were given daily for 8 days, and whole-body energy expenditure, respiratory quotient and adiposity were measured by indirect calorimetry at a resting state and exer
Sponsors
Institute
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) Healthy males of Japanese nationality between the ages of 18 and 30 with no exercise habits. 2) Subjects who can understand and comply with the rules written in protocol during the study period. 3) Subjects who got adequate explanation about the purpose and details of the examination, have the capacity to consent, voluntarily participate in understanding, and agree to participate in the examination in writing.
Exclusion criteria
Exclusion criteria: 1) Subjects with diseases of the gastrointestinal tract, liver, kidney, heart, and circulatory system that affect absorption, distribution, metabolism, and excretion of the test food. 2) Subjects with a history of the surgery considerable in the gastrointestinal tract site, for example, gastrectomy, stomach and intestines suturation, intestinal tract resection and so on (not including polypectomy and appendicectomy). 3) Subjects who has a history of seasonal allergies, perennial allergies, metal allergies, or asthma. 4) Subjects suspected of alcohol or drug dependence. 5) Subjects with problems with the diagnostic criteria for metabolic syndrome. 6) Subjects who taking medications (e.g., drugs for glucose or lipid metabolism, antihypertensive drugs, etc.). 7) Subjects who routinely consume health foods containing propolis or foods that affect lipid metabolism or body fat (including energy drinks and nutritional supplements). 8) Subjects who have a smoking habit (including e-cigarettes). 9) Subjects who another clinical trial or clinical research study within the past 84 days from the date consent was obtained. 10) Subjects who have donated 400 mL blood within the past 84 days, 200 mL blood within the past 28 days, or component blood donations (plasma and platelet components) within the past 14 days of obtaining consent. 11) Subjects who lead an irregular lifestyle (night shift workers, etc.) 12) Subjects who exercise on a daily basis (Subjects who have been performing light, sweaty exercise for at least 30 minutes a day, at least 2 days a week for at least 1 year.). 13) Subjects who may be exposed to extreme cold during the study period (e.g., travel to freezers or cold climates). 14) Subjects who are judged inappropriate as the subject by the subinvestigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whole body energy expenditure assessed by respiratory gas analysis | — |
Secondary
| Measure | Time frame |
|---|---|
| respiratory quotient, adiposity | — |
Countries
Japan
Contacts
Public ContactTakeshi Hashimoto
Ritsumeikan university Facuity of Sports and Health Science
Outcome results
None listed