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Efficacy and safety of high-intensity, low-frequency expiratory pressure load training in patients with chronic obstructive pulmonary disease

Efficacy and safety of high-intensity, low-frequency expiratory pressure load training in patients with chronic obstructive pulmonary disease - HILF-EPT study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000050746
Enrollment
5
Registered
2023-04-03
Start date
2023-04-03
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic obstructive pulmonary disease

Interventions

The patients will receive standard pulmonary rehabilitation in addition to EPT 30 times (5 times x 6 sets) per day, 3 days a week for 12 weeks. There is a 1 minute interval between each set, and the p

Sponsors

Japanese Red Cross Ishinomaki Hospital
Lead Sponsor
Ishinomaki COPD Network(ICON)
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients with COPD diagnosed according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria. 2) Patients underwent pulmonary rehabilitation, but complaining of progressive external dyspnea. 3) Patients whose conditions are stable and who are able to tolerate the 6-min walk test to ensure adequate evaluation. 4) Patients provided written informed consent to participate in this study.

Exclusion criteria

Exclusion criteria: 1) Patients with active infection. 2) Patients with severe heart disease. 3) Patients whose drug regimen was changed during this study. 4) Patients with a high risk of developing pneumothorax. 5) In addition to the above exclusion criteria, patients judged by their physician to be ineligible to participate in this study.

Design outcomes

Primary

MeasureTime frame
Change of the 6-min walk distance and the increase in the modified Borg scale at 12 weeks.

Secondary

MeasureTime frame
Respiratory muscle pressure, CAT, NRADL, body composition, handgrip strength, five times sit-to-stand test.

Countries

Japan

Contacts

Public ContactSeiichi Kobayashi

Japanese Red Cross Ishinomaki Hospital Department of Respiratory Medicine

skoba-thk@umin.ac.jp0225-21-7220

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026