Motor coordination of Laryngeal closure during swallowing in patients with Parkinson's disease (Four-dimensional evaluation using 320-row Area Detector CT)

Motor coordination of Laryngeal closure during swallowing in patients with Parkinson's disease (Four-dimensional evaluation using 320-row Area Detector CT) - Motor coordination of Laryngeal closure during swallowing in patients with Parkinson's disease (Four-dimensional evaluation using 320-row Area Detector CT)

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000050721

Enrollment

Registered

2023-03-30

Start date

2023-03-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson&#39

Interventions

320-ADCT imaging of swallowing

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with Parkinson's disease who were inpatients or outpatients at our Neurology Department. Patients who have been evaluated for swallowing function, are taking three meals orally. Patients are in stable general condition, and have given informed consent for this study.

Exclusion criteria

Exclusion criteria: 1. patients who are not medically stable 2. patients who are unable to perform voluntary movements due to impaired consciousness 3. patients who receive nutrition by tube feeding 4. other patients deemed inappropriate by the principal investigator and study coordinators

Design outcomes

Primary

Measure	Time frame
Start time of laryngeal closure, duration Laryngeal vestibular volume	—

Secondary

Measure	Time frame
Time of movement of various organs of swallowing other than the larynx Distance of hyoid-laryngeal movement Upper Esophageal sphincter opening area Pharyngeal volume Laryngeal penetration and aspiration during swallowing EAT-10/PILL-5 Correlation between CT swallowing index and severity of motor and non-motor symptoms of Parkinson's disease Correlation with brain MRI and dopamine and serotonin transporter imaging findings	—

Measure

Time frame

Time of movement of various organs of swallowing other than the larynx Distance of hyoid-laryngeal movement Upper Esophageal sphincter opening area Pharyngeal volume Laryngeal penetration and aspiration during swallowing EAT-10/PILL-5 Correlation between CT swallowing index and severity of motor and non-motor symptoms of Parkinson's disease Correlation with brain MRI and dopamine and serotonin transporter imaging findings

—

Countries

Japan

Contacts

Public ContactSeiko Shibata

Fujita Health University Dept. of Rehabilitation Medicine, School of Medicine

sshibata@fujita-hu.ac.jp0562-93-2167

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026

Motor coordination of Laryngeal closure during swallowing in patients with Parkinson&#39;s disease (Four-dimensional evaluation using 320-row Area Detector CT)