acute pancreatitis
Conditions
Interventions
None listed
Sponsors
Chiba University Hospital Emergency and Critical Care Medicine 1-8-1 Inohana, Chuo, Chiba 260-8677, Japan
RIKEN Center for Life Science Technologies, RIKEN Institute of Physical and Chemical Research.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adults (18 years of age or older) Patients diagnosed with acute pancreatitis using the Ministry of Health, Labour and Welfare's criteria for acute pancreatitis severity Patients newly admitted to the hospitals of the participating institution and expected to hospitalization for 48 hours or longer
Exclusion criteria
Exclusion criteria: Patients with inflammatory bowel disease Patients with diarrhea prior to admission Patients who have received antimicrobial agents for more than 1 week in the 2 months prior to admission Patients who are judged to be inappropriate as research subjects by the principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in various parameters of the intestinal microbiota, protein concentration in stool, and metabolite concentration | — |
Secondary
| Measure | Time frame |
|---|---|
| Relationship between each parameter and short- and long-term prognosis Correlation of each parameter with treatment details and clinical course during ICU stay Correlation between the amount of diarrhea and alpha-diversity parameters, protein concentration in each stool, and metabolite concentration Cluster analysis in patients with acute pancreatitis Development of artificial intelligence to predict patients' outcomes using collected clinical data and radiological information | — |
Countries
Japan
Contacts
Public ContactTakehiko Oami
Chiba University Hospital Emergency and Critical Care Medicine
Outcome results
None listed