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A prospective observational study on host immunity for development of novel immunotherapeutic strategy for treatment and prevention of postoperative infections

A prospective observational study on host immunity for development of novel immunotherapeutic strategy for treatment and prevention of postoperative infections - An observational study on immunity in patients with postoperative infections

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000050678
Enrollment
75
Registered
2023-03-27
Start date
2023-03-27
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Nagoya University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients scheduled for surgery for respiratory, gastrointestinal, cardiovascular, or other diseases. -Age: 20 and older

Exclusion criteria

Exclusion criteria: -Patients within 1 months of recovery from an acute infection -Patients with chronic hepatic disorders due to HBV or HCV infections. -HIV-positive patients -Patients previously treated with chemotherapy, immune checkpoint inhibitors, or radiation therapy for malignant tumors. -Patients with active multiple cancers. -Patients with active hematologic malignancies. -Patients with hemoglobin level <= 10 g/dL. -Patients after blood stem cell transplants, including bone marrow transplants. -Patients treated for co-morbidities with high-dose glucocorticoid, immunosuppressive drugs, or biological agents. -Elderly patients who are 90 years old or older. -Pregnant women.

Design outcomes

Primary

MeasureTime frame
1) Clinical outcome: Onset of postoperative infections within 30 days after surgery 2) Immunological outcome: Association between host immune characteristics and clinical outcomes—

Countries

Japan

Contacts

Public ContactYuichiro Shindo

Nagoya University Hospital Respiratory Medicine

yshindo@med.nagoya-u.ac.jp0527442167

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026